Alexa Fluor® 647 Mouse Anti-Human CD185 Antibody (S-R653)
SKU: 21971356014

Alexa Fluor® 647 Mouse Anti-Human CD185 Antibody (S-R653)

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Description

Alexa Fluor® 647 Mouse Anti-Human CD185 Antibody (S-R653)Product Specification Host Mouse Antigen CD185 Synonyms C X C chemokine receptor type 5; CXC R5; CXCR 5; Burkitt lymphoma receptor 1; Monocyte derived receptor 15 (MDR 15); BLR1; MDR15; CXCR5 Location Cell membrane Accession P32302 Clone Number S R653 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 02mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid

Product Specification


Host Mouse
Antigen CD185
Synonyms C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15 (MDR-15); BLR1; MDR15; CXCR5
Location Cell membrane
Accession P32302
Clone Number S-R653
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample human PBMC
Purification Protein G
Concentration 0.02mg/ml
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD185, also known as CXCR5 or Burkitt lymphoma receptor 1 (BLR1), is a 42 kD G-protein coupled receptor with seven transmembrane regions. It belongs to the CXC chemokine receptor family and is a specific receptor for the CXC chemokine CXCL13. CD185 is expressed on mature B cells, follicular helper T cells (Tfh), and certain memory T cells. It plays a critical role in lymphocyte trafficking, particularly in the migration of T cells into B cell follicles of germinal centers, making it an established marker of follicular helper T cells. Additionally, CD185 is involved in B cell migration and maturation in lymph nodes and spleen. Its expression has been reported in various tissues, including human blood, salivary glands, and lymphatic organs.

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SKU: 21971356014

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Virginia H.
Lowell, US
★★★★★ 1
Worst Experience of my Life
My Epson printer had problems with it's software in early mid April, while trying to resolve the software glitch which I could not, I found that every picture I had scanned for some time had lines running through it and no cleaning process or other process that Epson had would get rid of it, and everything I had scanned for my project, was ruined. I sent the machine to Asurion following their instructions and explaining the issues. They sent it back to me after a month saying they had double checked and fixed everything, I spent some time setting it all back up, only to find that exactly the same two issues were still present and the machine was unusable. I sent in a second request, this time they sent it back to me a month later saying they couldn't find anything wrong with it. Hooked it up again, same problem. I complained numerous times asked for them to warranty the item; they would not unless I sent it back to them and they kept it and then they would give me a credit on my amazon account to buy a new one. I packed it up and drove to UPS a third time and mailed it back to them, after about three weeks they sent me a note that they had it and that they were sending it back to me as they couldn't find anything wrong. Three times I ha filled out their entire sheet with product, date of purchase, problems detailed, receipts, picture of the lines in the photos that it was making over all the scanned photos. Then after two weeks of back and forth they sent me a message telling me they couldn't warranty it until I filled all this information out again on line. Then they told me they couldn't read the tiny print off the receipt printed off the Amazon site, which I cannot change. I then blew up the receipts and circled everything and sent it back to them again...of course they already had now five copies of this same information, they had paid for postage three times to NY and back to fix it and they still aren't able to process a payment to me????? Finally I get a call from a gentleman telling me that I will have a credit to my Amazon Card in 72 hours. Great. Then he calls me back the next day and says the warranty team has decided they would not warranty the item and credit me but they will mail me a check in 7 to 10 days. After over four months of this I received a check...will it bounce? I don't know yet. My project that I was working on was for my mother's Celebration of Life, I could not do what I wanted to do for her, this caused me emotional pain, as well as the obvious frustration of four months of aggravation and complete and total ineptitude on their part.
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Reviewed in the United States on August 10, 2024
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Sublimation ink
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New York, US
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★★★★★ 5
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Great quality!!!
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