IL-28A/IFN-λ2 Protein, Mouse
SKU: 1529440896

IL-28A/IFN-λ2 Protein, Mouse

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Description

IL-28A/IFN-λ2 Protein, MouseProduct Specification Species Mouse Synonyms Interferon lambda 2; IFN lambda 2; Interleukin 28A; IL 28A; Accession Q4VK74 Amino Acid Sequence Asp20 Val193 Expression System E. coli Molecular Weight 20 kDa (Reducing) Purity >95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 150mM NaCl, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size

Product Specification


Species Mouse
Synonyms Interferon lambda-2; IFN-lambda-2; Interleukin-28A; IL-28A;
Accession Q4VK74
Amino Acid Sequence

Asp20-Val193
Expression System E.coli
Molecular Weight

20 kDa (Reducing)
Purity >95% by SDS-PAGE and HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM Tris, 150mM NaCl, pH8.0
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

Nat Immunol. 2003 Jan;4(1):63-8.

Background

Interferon lambda 2 (IFN-λ2), also known as IL-28A, is a member of the type III interferon family, which also includes IFN-λ1 and IFN-λ3. IFN-λ2 plays a crucial role in the innate immune response to viral infections and has been shown to exhibit antiviral activity against a variety of viruses, including hepatitis C virus, influenza virus, and others. It signals through the IFN-λ receptor complex, leading to the activation of JAK-STAT signaling pathways and the induction of interferon-stimulated genes (ISGs) that contribute to the antiviral defense mechanisms. IFN-λ2 is primarily produced by immune cells, such as dendritic cells and macrophages, in response to viral stimuli and functions as a key mediator of the host's defense against viral pathogens.

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SKU: 1529440896

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Nygilyo
Alexandria, US
★★★★★ 2
arrived damaged
Format: Paperback, Format: Paperback
poor packing, but good read
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Reviewed in the United States on May 14, 2024
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Forrest F.
Waukegan, US
★★★★★ 5
The history is unpleasant and therefore worth knowing.
It's a wonderfully enlightening history of how European explorers visited, settled in, conquered, and exploited other continents with unparalleled cruelty in the name of power, greed, and their "loving" religion that brought them misery, exploitation and, all too often, abject slavery.
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Reviewed in the United States on March 9, 2025
M
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Marianne Mountain Dawn Scofield
Alexandria, US
★★★★★ 5
Wonderful History Lessons
I ordered this book to use for a college paper I was writing and found it fascinating. I enjoyed the content and learned much from it. The history is written in a manner that for those people that either don't read much or don't like to read (yes, there are a few people out there), it will draw you in and make you question the history lessons we suffered through in high school.
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Reviewed in the United States on January 11, 2013
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Amazon Customer
Los Angeles, US
★★★★★ 5
Excellent and Eye Opening
Where but in America could white men kill 2,ooo,ooo people to prove they are more civilized ?
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Reviewed in the United States on March 16, 2017
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Ken Kardash
Carnegie, US
★★★★★ 4
Rediscovering America
This is an eye-opening, scholarly rebuttal to common perceptions about native American society before and after the European invasion. Ronald Wright makes no secret of his bias in favor of the people who were here first; in fact, he enhances the impact of what for many will be new information by presenting this extraordinary history from the point of view of the conquered. He also makes clear how large a part of the conquest was due to immune system rather than military deficiencies: if smallpox and other diseases had not done killed most of the native population, the facts recounted here suggest that history, particularly in South America, may have evolved quite differently. In undertaking the massive task of recounting the invasion of all of the Americas, some selectivity is inevitable. Wright has chosen to focus on the story of five distinct native groups: Aztec, Maya, Inca, Cherokee and Iroquois. He then arbitrarily subdivides the story into three consecutive time periods: Conquest, Resistance and Rebirth. After the physical and political annihilation recounted in the first two sections, the title of the third may seem overly optimistic, particularly for the Guatemalan Maya. However, the concluding tone is more conciliatory and hopeful than mournful, particularly in the Afterword that updates matters to 2005, 13 years after the original publication date. The astounding amount of research involved in producing this admittedly selective overview is well-indexed and annotated. My only quibble is that Wright, obviously an expert in the field of native culture, sometimes borders on the compulsive in matters of linguistic authenticity. I did not buy this book to learn ancient native languages, let alone their pronunciation, and at times I found the inclusion of such trivia distracted from rather than enhanced the otherwise convincing scholarship. This obsession with accuracy is commendable, but after getting it out of his system in the Author's note, his amazing narrative would have been no less compelling if he stuck to the language of his contemporary audience. Also, for an author who has settled in British Columbia, it is strangely disappointing that the rich history of the Pacific Northwest coastal natives was not among those he chose to examine. I had read Charles Mann's "1491" prior to this book and found it primed my interest in the subject; both are excellent introductions to the reality of pre-Columbian American societies, but Stolen Continents provides more of a historical context for what has become of them.
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Reviewed in the United States on October 13, 2008

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